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Microstrip line based non-invasive glucose meter for continuous glucose monitoring

Technology title

Microstrip line based non-invasive glucose meter for continuous glucose monitoringMicrostrip line based non-invasive glucose meter for continuous glucose monitoring

Technology overview

This invention introduces a microwave-based glucose meter designed for non-invasive monitoring. It applies transmission line theory, where the sensing target, such as a finger, serves as the substrate or dielectric medium between conductors to achieve high field density and sensitivity. Various configurations such as rings and wrist bands can be used. Patterned transmission lines and ground planes further enhance sensitivity for accurate, real-time glucose detection.

 

Technology specifications

The technology is realised by having a microstrip line (MLIN) built around a finger with the finger serving as the substrate of the MLIN. Signal is input from the tip of the finger. The signal line is on one side of the finger, and the ground plane is on the other side. The return loss of the microstrip is then measured to determine the glucose concentrations.

 

In our proposed approach, the sensitivity is increased significantly by:

  • the dense field between the transmission line and the ground plane for sensing; and
  • the patterned transmission line and patterned ground plane.

The sensor can be worn as a ring, finger stall or bracelet. Other similar products have low penetration depth, and their readings are affected by factors such as body temperature and hydration.

Sector

Healthcare and diagnostics

Market opportunity

The global diabetes prevalence is estimated to be 9.3% in 2019 and is expected to rise to 10.2% by 2030 and 10.9% by 2045. Although there is no cure for diabetes, regular blood glucose monitoring and appropriate medication can control the symptoms.

 

Electrochemical glucose meters are accepted as being the most accurate and reliable glucose measurement devices. However, they are invasive, and patients need to take three to six measurements daily. As a result, their nervous system may be damaged due to long-term usage.

 

There are several proposed approaches for non-invasive glucose monitoring, mainly based on optical, transdermal and electrochemical techniques. Due to the nature of these technologies, the proposed approaches are not suitable for continuous monitoring.

Applications

Key applications include continuous non-invasive glucose monitoring of diabetic patients.

Customer benefits

This technology offers a non-invasive alternative method, which could be used to develop a continuous glucose monitoring sensor device with high sensitivity.

Technology readiness level

TRL 5

Ideal collaboration partner

Ideal collaboration partners include:

  • Hospitals
  • Medical device companies
Collaboration mode

This technology is suitable for multiple collaboration modes including licensing and test-bedding.